Which option best describes a containment configuration suitable for hazardous compounding?

Which option best describes a containment configuration suitable for hazardous compounding?

• A. Negative-pressure room with external exhaust
• B. Positive-pressure room
• C. Unventilated room
• D. Shared air with general space

Answer: (A)

Containment for hazardous compounding relies on controlling airflow to prevent exposure. A negative-pressure room with external exhaust keeps the room at a lower pressure than surrounding spaces, so air flows into the room and is then vented outside. This setup captures and removes any airborne contaminants, minimizing their escape into the rest of the facility. By contrast, a positive-pressure room would push air into adjacent areas, increasing exposure risk, while an unventilated room or shared-air space offers no ventilation control and would allow hazards to spread.

Containment for hazardous compounding relies on controlling airflow to prevent exposure. A negative-pressure room with external exhaust keeps the room at a lower pressure than surrounding spaces, so air flows into the room and is then vented outside. This setup captures and removes any airborne contaminants, minimizing their escape into the rest of the facility. By contrast, a positive-pressure room would push air into adjacent areas, increasing exposure risk, while an unventilated room or shared-air space offers no ventilation control and would allow hazards to spread.